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The American Medical Association, founded in 1847 in Chicago, is dedicated to the promotion of improved public health, scientific advancement, and patient and doctor relationships. The association includes MDs, Dos and medical students throughout the United States. The association holds a lot of lobbying power and has worked against such movements as the health maintenance organizations during the Great Depression and Medicare in the 1950s and 1960s. The organization also supported certain movements such as the War on Drugs. The association has annual meetings to discuss their accomplishments and their future goals and projects. In addition to their work for patients and doctors AMA also published JAMA, Journal of the American Medical Association, to further promote research. This publication has the largest circulation in the world of any weekly medical journal.