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In October of 1979, the United States allowed Mohammad Reza Pahlavi, the Shah of Iran, to enter the country for cancer treatment. This made Ruhollah Khomeini, the Grand Ayatollah of Iran and his people angry because the Shah was supposed to stand trial in Iran. In response, a group of college students took control of the American Embassy in Tehran with support from the Ayatollah and held 52 people hostage in what is known as the Iran hostage crisis. The crisis was resolved in January 1981 via the Algeria Declaration and the hostages were freed, but afterwards the relationship between Iran and the United States was damaged and the U.S. imposed sanctions against Iran.
Iran hostage crisis. (2018). Retrieved from https://en.wikipedia.org/wiki/Iran_hostage_crisis