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Twenty Grand was an American racing horse in the 1930s and 1940s. He was owned and bred by Helen Hay Whitney's Greentree Stable and won 14 out of 25 races in his lifetime, including the Kentucky Derby. He is notable for being part of the "big four," which were the top four racing horses at the time. Twenty Grand was elected to the National Museum of Racing and Hall of Fame and is also ranked at number 52 in the top 100 US thoroughbred champions of the 20th century in Blood-Horse.